GntP

• Description: gluconate permease
  
  

Gene name	gntP
Synonyms
Essential	no
Product	gluconate permease
Function	gluconate uptake
Gene expression levels in SubtiExpress: gntP
Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism
MW, pI	46 kDa, 8.098
Gene length, protein length	1344 bp, 448 aa
Immediate neighbours	gntK, gntZ
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transporters/ other, utilization of specific carbon sources, membrane proteins

This gene is a member of the following regulons

AbrB regulon, CcpA regulon, GntR regulon

The gene

Basic information

• Locus tag: BSU40070

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: gntP permease family (according to Swiss-Prot)

• Paralogous protein(s): YojA

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P12012

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: gntR-gntK-gntP-gntZ PubMed1 PubMed2

• Expression browser: gntP PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • induced by gluconate (GntR) PubMed
  • repressed by glucose (CcpA) PubMed

• Regulatory mechanism:
  • GntR: transcription repression PubMed
  • CcpA: transcription repression PubMed
  • AbrB: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed