YrkP

• Description: two-component response regulator
  
  

Gene name	yrkP
Synonyms
Essential	no
Product	two-component response regulator
Function	unknown
Gene expression levels in SubtiExpress: yrkP
Interactions involving this protein in SubtInteract: YrkP
MW, pI	26 kDa, 5.694
Gene length, protein length	693 bp, 231 aa
Immediate neighbours	yrkQ, yrkO
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transcription factors and their control, membrane proteins, phosphoproteins

This gene is a member of the following regulons

YrkP regulon

The gene

Basic information

• Locus tag: BSU26430

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: OmpR family of two-component response regulators

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification: phosphorylated by YrkQ on an Asp residue

• Cofactor(s):

• Effectors of protein activity: phosphorylation likely affects DNA-binding activity

• Interactions: YrkQ-YrkP

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P54443

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: yrkP-yrkQ-yrkR PubMed

• Expression browser: yrkP PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:
  • YrkP: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Mitsuo Ogura, Taku Ohsawa, Teruo Tanaka
Identification of the sequences recognized by the Bacillus subtilis response regulator YrkP.
Biosci Biotechnol Biochem: 2008, 72(1);186-96
[PubMed:18175906] [WorldCat.org] [DOI] (I p)

C Fabret, V A Feher, J A Hoch
Two-component signal transduction in Bacillus subtilis: how one organism sees its world.
J Bacteriol: 1999, 181(7);1975-83
[PubMed:10094672] [WorldCat.org] [DOI] (P p)