GerT

• Description: spore coat protein, involved in germination
  
  

Gene name	gerT
Synonyms	yozR
Essential	no
Product	spore coat protein
Function	germination
Gene expression levels in SubtiExpress: gerT
MW, pI	18 kDa, 6.342
Gene length, protein length	471 bp, 157 aa
Immediate neighbours	yojE, yojB
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

sporulation proteins, germination, membrane proteins

This gene is a member of the following regulons

SigK regulon

The gene

Basic information

• Locus tag: BSU19490

Phenotypes of a mutant

• mutants respond poorly to multiple germinants, impaired in early stage of germination PubMed

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: eamA transporter family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane (according to Swiss-Prot), first assembled in foci, then spread around the developing spore in a CotE-dependent manner PubMed

Database entries

• Structure:

• UniProt: Q7WY67

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: gerT (according to DBTBS)

• Expression browser: gerT PubMed

• Sigma factor: SigK PubMed

• Regulation:
  • expressed late during sporulation in the mother cell (SigK, GerE) PubMed

• Regulatory mechanism:
  • GerE: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Caitlin C Ferguson, Amy H Camp, Richard Losick
gerT, a newly discovered germination gene under the control of the sporulation transcription factor sigmaK in Bacillus subtilis.
J Bacteriol: 2007, 189(21);7681-9
[PubMed:17720779] [WorldCat.org] [DOI] (P p)