UxaA

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  • Description: altronate hydrolase

Gene name uxaA
Synonyms yjmJ
Essential no
Product altronate hydrolase
Function hexuronate utilization
Gene expression levels in SubtiExpress: uxaA
MW, pI 54 kDa, 5.781
Gene length, protein length 1491 bp, 497 aa
Immediate neighbours uxaB, yjnA
Sequences Protein DNA DNA_with_flanks
Genetic context
UxaA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
UxaA expression.png


























Categories containing this gene/protein

utilization of specific carbon sources, sporulation proteins

This gene is a member of the following regulons

CcpA regulon, ExuR regulon, SigE regulon

The gene

Basic information

  • Locus tag: BSU12390

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: D-altronate = 2-dehydro-3-deoxy-D-gluconate + H2O (according to Swiss-Prot)
  • Protein family: uxaA family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Y Miwa, A Nakata, A Ogiwara, M Yamamoto, Y Fujita
Evaluation and characterization of catabolite-responsive elements (cre) of Bacillus subtilis.
Nucleic Acids Res: 2000, 28(5);1206-10
[PubMed:10666464] [WorldCat.org] [DOI] (I p)

K R Mekjian, E M Bryan, B W Beall, C P Moran
Regulation of hexuronate utilization in Bacillus subtilis.
J Bacteriol: 1999, 181(2);426-33
[PubMed:9882655] [WorldCat.org] [DOI] (P p)

Carlo Rivolta, Blazenka Soldo, Vladimir Lazarevic, Bernard Joris, Catherine Mauël, Dimitri Karamat
A 35.7 kb DNA fragment from the Bacillus subtilis chromosome containing a putative 12.3 kb operon involved in hexuronate catabolism and a perfectly symmetrical hypothetical catabolite-responsive element.
Microbiology (Reading): 1998, 144 ( Pt 4);877-884
[PubMed:9579062] [WorldCat.org] [DOI] (P p)