YjcD

• Description: similar to ATP-dependent DNA helicase
  
  

Gene name	yjcD
Synonyms
Essential	no
Product	unknown
Function	unknown
Gene expression levels in SubtiExpress: yjcD
Metabolic function and regulation of this protein in SubtiPathways: Folate
MW, pI	86 kDa, 8.015
Gene length, protein length	2277 bp, 759 aa
Immediate neighbours	spoVIF, yjzE
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

DNA repair/ recombination

The gene

Basic information

• Locus tag: BSU11820

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: uvrD-like helicase C-terminal domain (according to Swiss-Prot)

• Paralogous protein(s): PcrA

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cytoplasm (according to Swiss-Prot)

Database entries

• Structure:
  • 2PJR (PcrA product complex, complex with sulphate ion, Geobacillus stearothermophilus, 36% identity, 55% similarity)
  • 1PJR (PcrA substrate complex, complex with DNA, Geobacillus stearothermophilus, 36% identity, 55% similarity)

• UniProt: O31626

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: yjcD PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

S S Velankar, P Soultanas, M S Dillingham, H S Subramanya, D B Wigley
Crystal structures of complexes of PcrA DNA helicase with a DNA substrate indicate an inchworm mechanism.
Cell: 1999, 97(1);75-84
[PubMed:10199404] [WorldCat.org] [DOI] (P p)