SecY

• Description: preprotein translocase subunit, universally conserved protein
  
  

Gene name	secY
Synonyms
Essential	yes PubMed
Product	preprotein translocase subunit
Function	protein secretion
Gene expression levels in SubtiExpress: secY
Interactions involving this protein in SubtInteract: SecY
Metabolic function and regulation of this protein in SubtiPathways: Protein secretion
MW, pI	47 kDa, 10.209
Gene length, protein length	1293 bp, 431 aa
Immediate neighbours	rplO, adk
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

protein secretion, essential genes, membrane proteins, universally conserved proteins

This gene is a member of the following regulons

stringent response

The gene

Basic information

• Locus tag: BSU01360

Phenotypes of a mutant

essential PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: secY/SEC61-alpha family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • (SecY-SecE-SecG)2-SecA2 PubMed
  • FloT-SecY PubMed

• Localization: membrane PubMed

Database entries

• Structure: 3DL8 (structure of the (SecY-SecE-SecG)-SecA complex PubMed

• UniProt: P16336

• KEGG entry: [2]

• E.C. number:

Additional information

universally conserved protein

Expression and regulation

• Operon: rplO-secY-adk-map

• Expression browser: secY PubMed

• Sigma factor:

• Regulation:
  • RelA dependent downregulation (Class I) during stringent response PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant: Pspac-secY PubMed

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: