YxbA

• Description: putative D-aspartate ligase
  
  

Gene name	yxbA
Synonyms	yxaO, aslA
Essential	no
Product	putative D-aspartate ligase
Function	unknown
Gene expression levels in SubtiExpress: yxbA
Metabolic function and regulation of this protein in SubtiPathways: Asp, Asn
MW, pI	10 kDa, 4.433
Gene length, protein length	267 bp, 89 aa
Immediate neighbours	yxbB, yxnB
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

poorly characterized/ putative enzymes, sporulation proteins

This gene is a member of the following regulons

AbrB regulon, CodY regulon

The gene

Basic information

• Locus tag: BSU39900

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P46325

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon:
  • yxbB-yxbA-yxnB-asnH-yxaM PubMed
  • yxbB-yxbA-yxnB PubMed

• Expression browser: yxbA PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • repressed by glucose (8-fold) PubMed
  • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
  • repressed during logrithmic growth (AbrB) PubMed

• Regulatory mechanism:
  • CodY: transcription repression PubMed
  • AbrB: transcription repression PubMed

• Additional information:
  • the tricistronic yxbB-yxbA-yxnB transcript is extremely stable, and stability is mediated by a 5'-proximal long sequence triplication preceding the yxbB open reading frame PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: