RapD

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Gene name rapD
Synonyms ywpA
Essential no
Product response regulator aspartate phosphatase
Function control of ComA-dependent gene expression
Gene expression levels in SubtiExpress: rapD
Interactions involving this protein in SubtInteract: RapD
MW, pI 41 kDa, 7.691
Gene length, protein length 1062 bp, 354 aa
Immediate neighbours ywpB, flhP
Sequences Protein DNA DNA_with_flanks
Genetic context
RapD context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
RapD expression.png
























Categories containing this gene/protein

genetic competence, protein modification, transcription factors and their control, quorum sensing, cell envelope stress proteins (controlled by SigM, V, W, X, Y)

This gene is a member of the following regulons

RghR regulon, SigM regulon, SigX regulon

The gene

Basic information

  • Locus tag: BSU36380

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: control of ComA-dependent gene expression PubMed
  • Protein family: RAP family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Warawan Eiamphungporn, John D Helmann
The Bacillus subtilis sigma(M) regulon and its contribution to cell envelope stress responses.
Mol Microbiol: 2008, 67(4);830-48
[PubMed:18179421] [WorldCat.org] [DOI] (P p)

Mitsuo Ogura, Yasutaro Fujita
Bacillus subtilis rapD, a direct target of transcription repression by RghR, negatively regulates srfA expression.
FEMS Microbiol Lett: 2007, 268(1);73-80
[PubMed:17227471] [WorldCat.org] [DOI] (P p)

X Huang, J D Helmann
Identification of target promoters for the Bacillus subtilis sigma X factor using a consensus-directed search.
J Mol Biol: 1998, 279(1);165-73
[PubMed:9636707] [WorldCat.org] [DOI] (P p)