LutB

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  • Description: lactate catabolic enzyme

Gene name lutB
Synonyms yvfW
Essential no
Product lactate oxidase
Function lactate utilization
Gene expression levels in SubtiExpress: lutB
Metabolic function and regulation of this protein in SubtiPathways:
Central C-metabolism
MW, pI 53 kDa, 5.848
Gene length, protein length 1437 bp, 479 aa
Immediate neighbours lutC, lutA
Sequences Protein DNA DNA_with_flanks
Genetic context
YvfW context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
LutB expression.png




























Categories containing this gene/protein

utilization of specific carbon sources, phosphoproteins

This gene is a member of the following regulons

FbpB regulon, FsrA regulon, LutR regulon, SinR regulon

The gene

Basic information

  • Locus tag: BSU34040

Phenotypes of a mutant

no growth with lactate as the single carbon source PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: oxidation of lactate to pyruvate PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
    • phosphorylated on Arg-33 PubMed
  • Cofactor(s): contains an iron-sulfur cluster
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Richard Losick, Harvard Univ., Cambridge, USA homepage

Your additional remarks

References