NhaK

• Description: cation/H+ antiporter
  
  

Gene name	nhaK
Synonyms	yvgP
Essential	no
Product	cation/H+ antiporter
Function	monovalent cation export
Gene expression levels in SubtiExpress: nhaK
MW, pI	75 kDa, 9.222
Gene length, protein length	2010 bp, 670 aa
Immediate neighbours	yvgO, cysJ
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transporters/ other, metal ion homeostasis (K, Na, Ca, Mg), membrane proteins

The gene

Basic information

• Locus tag: BSU33420

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: export of Na(+), K(+), Li(+), Rb(+)

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O32212

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: nhaK PubMed

• Expression browser: nhaK PubMed

• Sigma factor:

• Regulation: constitutive, expression increases in the presence of Na(+) and K(+) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Makoto Fujisawa, Ayumi Kusumoto, Yuko Wada, Takahiro Tsuchiya, Masahiro Ito
NhaK, a novel monovalent cation/H+ antiporter of Bacillus subtilis.
Arch Microbiol: 2005, 183(6);411-20
[PubMed:16021482] [WorldCat.org] [DOI] (P p)