MtnN

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  • Description: methylthioadenosine nucleosidase

Gene name mtnN
Synonyms yrrU, mtn
Essential no
Product methylthioadenosine nucleosidase
Function methionine salvage
Gene expression levels in SubtiExpress: mtnN
Metabolic function and regulation of this protein in SubtiPathways:
Cys, Met & Sulfate assimilation
MW, pI 25 kDa, 4.844
Gene length, protein length 693 bp, 231 aa
Immediate neighbours mccA, yrrT
Sequences Protein DNA DNA_with_flanks
Genetic context
Mtn context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
MtnN expression.png




























Categories containing this gene/protein

biosynthesis/ acquisition of amino acids

This gene is a member of the following regulons

CymR regulon, Spx regulon

The gene

Basic information

  • Locus tag: BSU27270

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: S-adenosyl-L-homocysteine + H2O = S-(5-deoxy-D-ribos-5-yl)-L-homocysteine + adenine (according to Swiss-Prot)
  • Protein family: MtnN subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 1JYS (from Escherichia coli, 51% identity, 70% similarity) PubMed
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • repressed in the presence of cysteine (CymR) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References