ResC

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  • Description: part of heam translocase, required for cytochrome c synthesis

Gene name resC
Synonyms ypxC
Essential yes PubMed
Product part of the ResB-ResC haem translocase
Function cytochrome c biogenesis
Gene expression levels in SubtiExpress: resC
Interactions involving this protein in SubtInteract: ResC
MW, pI 39 kDa, 9.564
Gene length, protein length 1056 bp, 352 aa
Immediate neighbours resD, resB
Sequences Protein DNA DNA_with_flanks
Genetic context
ResC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
ResC expression.png
























Categories containing this gene/protein

respiration, essential genes, membrane proteins

This gene is a member of the following regulons

CcpA regulon, PhoP regulon, ResD regulon

The gene

Basic information

  • Locus tag: BSU23130

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: haem-binding protein, translocation of haem from the cytoplasmic to the extracytoplasmic site of the membrane PubMed
  • Protein family: ccmF/cycK/ccl1/nrfE/ccsA family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed under anaerobic conditions (ResD) PubMed
    • expressed under conditions of phosphate limitation (PhoP) PubMed
    • repressed by glucose (CcpA) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References