YjcD

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  • Description: similar to ATP-dependent DNA helicase

Gene name yjcD
Synonyms
Essential no
Product unknown
Function unknown
Gene expression levels in SubtiExpress: yjcD
Metabolic function and regulation of this protein in SubtiPathways:
Folate
MW, pI 86 kDa, 8.015
Gene length, protein length 2277 bp, 759 aa
Immediate neighbours spoVIF, yjzE
Sequences Protein DNA DNA_with_flanks
Genetic context
YjcD context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YjcD expression.png




























Categories containing this gene/protein

DNA repair/ recombination

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU11820

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: uvrD-like helicase C-terminal domain (according to Swiss-Prot)
  • Paralogous protein(s): PcrA

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
    • 2PJR (PcrA product complex, complex with sulphate ion, Geobacillus stearothermophilus, 36% identity, 55% similarity)
    • 1PJR (PcrA substrate complex, complex with DNA, Geobacillus stearothermophilus, 36% identity, 55% similarity)
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

S S Velankar, P Soultanas, M S Dillingham, H S Subramanya, D B Wigley
Crystal structures of complexes of PcrA DNA helicase with a DNA substrate indicate an inchworm mechanism.
Cell: 1999, 97(1);75-84
[PubMed:10199404] [WorldCat.org] [DOI] (P p)