HxlR

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Gene name hxlR
Synonyms yckH
Essential no
Product MarR/DUF24 family transcription activator
Function regulation of the ribulose monophosphate pathway
Gene expression levels in SubtiExpress: hxlR
MW, pI 14 kDa, 6.358
Gene length, protein length 360 bp, 120 aa
Immediate neighbours hxlA, srfAA
Sequences Protein DNA DNA_with_flanks
Genetic context
HxlR context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
HxlR expression.png


























Categories containing this gene/protein

transcription factors and their control, resistance against oxidative and electrophile stress

This gene is a member of the following regulons

The HxlR regulon:

The gene

Basic information

  • Locus tag: BSU03470

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: transcription activation of the ribulose monophosphate pathway for formaldehyde fixation and detoxification
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity: formaldehyde stimulates transcription activation by HxlR

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: hxlR (according to DBTBS)
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References