Rho

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  • Description: transcriptional termination protein

Gene name rho
Synonyms
Essential no
Product transcriptional termination protein
Function transcriptional termination
Gene expression levels in SubtiExpress: rho
Interactions involving this protein in SubtInteract: Rho
MW, pI 48 kDa, 6.865
Gene length, protein length 1281 bp, 427 aa
Immediate neighbours rpmE, glpX
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
Rho context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Rho expression.png















Categories containing this gene/protein

transcription

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU37080

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: rho family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Marc Boudvillain, Nara Figueroa-Bossi, Lionello Bossi
Terminator still moving forward: expanding roles for Rho factor.
Curr Opin Microbiol: 2013, 16(2);118-24
[PubMed:23347833] [WorldCat.org] [DOI] (I p)

M Sofia Ciampi
Rho-dependent terminators and transcription termination.
Microbiology (Reading): 2006, 152(Pt 9);2515-2528
[PubMed:16946247] [WorldCat.org] [DOI] (P p)

John P Richardson
Loading Rho to terminate transcription.
Cell: 2003, 114(2);157-9
[PubMed:12887917] [WorldCat.org] [DOI] (P p)

J P Richardson
Structural organization of transcription termination factor Rho.
J Biol Chem: 1996, 271(3);1251-4
[PubMed:8576105] [WorldCat.org] [DOI] (P p)


Original publications

Additional publications: PubMed

Pierre Nicolas, Ulrike Mäder, Etienne Dervyn, Tatiana Rochat, Aurélie Leduc, Nathalie Pigeonneau, Elena Bidnenko, Elodie Marchadier, Mark Hoebeke, Stéphane Aymerich, Dörte Becher, Paola Bisicchia, Eric Botella, Olivier Delumeau, Geoff Doherty, Emma L Denham, Mark J Fogg, Vincent Fromion, Anne Goelzer, Annette Hansen, Elisabeth Härtig, Colin R Harwood, Georg Homuth, Hanne Jarmer, Matthieu Jules, Edda Klipp, Ludovic Le Chat, François Lecointe, Peter Lewis, Wolfram Liebermeister, Anika March, Ruben A T Mars, Priyanka Nannapaneni, David Noone, Susanne Pohl, Bernd Rinn, Frank Rügheimer, Praveen K Sappa, Franck Samson, Marc Schaffer, Benno Schwikowski, Leif Steil, Jörg Stülke, Thomas Wiegert, Kevin M Devine, Anthony J Wilkinson, Jan Maarten van Dijl, Michael Hecker, Uwe Völker, Philippe Bessières, Philippe Noirot
Condition-dependent transcriptome reveals high-level regulatory architecture in Bacillus subtilis.
Science: 2012, 335(6072);1103-6
[PubMed:22383849] [WorldCat.org] [DOI] (I p)

Vitaly Epshtein, Dipak Dutta, Joseph Wade, Evgeny Nudler
An allosteric mechanism of Rho-dependent transcription termination.
Nature: 2010, 463(7278);245-9
[PubMed:20075920] [WorldCat.org] [DOI] (I p)

Emmanuel Skordalakes, James M Berger
Structure of the Rho transcription terminator: mechanism of mRNA recognition and helicase loading.
Cell: 2003, 114(1);135-46
[PubMed:12859904] [WorldCat.org] [DOI] (P p)

H Yakhnin, J E Babiarz, A V Yakhnin, P Babitzke
Expression of the Bacillus subtilis trpEDCFBA operon is influenced by translational coupling and Rho termination factor.
J Bacteriol: 2001, 183(20);5918-26
[PubMed:11566991] [WorldCat.org] [DOI] (P p)

C J Ingham, J Dennis, P A Furneaux
Autogenous regulation of transcription termination factor Rho and the requirement for Nus factors in Bacillus subtilis.
Mol Microbiol: 1999, 31(2);651-63
[PubMed:10027981] [WorldCat.org] [DOI] (P p)