YjbI

• Description: truncated hemoglobin, NO protection
  
  

Gene name	yjbI
Synonyms
Essential	no
Product	truncated hemoglobin
Function	protection against NO, thiol redox homeostasis
Gene expression levels in SubtiExpress: yjbI
MW, pI	14 kDa, 5.173
Gene length, protein length	396 bp, 132 aa
Immediate neighbours	yjbH, cwlQ
Sequences	Protein DNA Advanced_DNA
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

resistance against other toxic compounds (nitric oxide, phenolic acids, flavonoids, oxalate)

The gene

Basic information

• Locus tag: BSU11560

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: binds sulfide with high affinity PubMed

• Protein family: protozoan/cyanobacterial globin family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information: K(D) for hydrogen sulfide = 5.0x10(6) M-1 PubMed

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 1UX8

• UniProt: O31607

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: yjbI-yjbH PubMed

• Expression browser: yjbI PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:
  • 1A864 ( yjbI::spec), PubMed, available at BGSC

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Andrea Lapini, Mariangela Di Donato, Barbara Patrizi, Agnese Marcelli, Manuela Lima, Roberto Righini, Paolo Foggi, Natascia Sciamanna, Alberto Boffi
Carbon monoxide recombination dynamics in truncated hemoglobins studied with visible-pump midIR-probe spectroscopy.
J Phys Chem B: 2012, 116(30);8753-61
[PubMed:22759230] [WorldCat.org] [DOI] (I p)

Francesco P Nicoletti, Alessandra Comandini, Alessandra Bonamore, Leonardo Boechi, Fernando Martin Boubeta, Alessandro Feis, Giulietta Smulevich, Alberto Boffi
Sulfide binding properties of truncated hemoglobins.
Biochemistry: 2010, 49(10);2269-78
[PubMed:20102180] [WorldCat.org] [DOI] (I p)

Leonardo Boechi, Pau Arroyo Mañez, F Javier Luque, Marcelo A Marti, Dario A Estrin
Unraveling the molecular basis for ligand binding in truncated hemoglobins: the trHbO Bacillus subtilis case.
Proteins: 2010, 78(4);962-70
[PubMed:19899166] [WorldCat.org] [DOI] (I p)

Annika Rogstam, Jonas T Larsson, Peter Kjelgaard, Claes von Wachenfeldt
Mechanisms of adaptation to nitrosative stress in Bacillus subtilis.
J Bacteriol: 2007, 189(8);3063-71
[PubMed:17293416] [WorldCat.org] [DOI] (P p)