RecN

• Description: DNA repair and genetic recombination
  
  

Gene name	recN
Synonyms
Essential	no
Product	unknown
Function	DNA repair and genetic recombination
Gene expression levels in SubtiExpress: recN
MW, pI	64 kDa, 4.802
Gene length, protein length	1728 bp, 576 aa
Immediate neighbours	spoIVB, ahrC
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

DNA repair/ recombination, membrane proteins

The gene

Basic information

• Locus tag: BSU24240

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:
  • RecN stimulates polymerizing activity of PnpA PubMed

• Protein family: recN family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • nucleoid (Multiple) PubMed
  • evenly distributed in growing cells PubMed
  • upon DNA damage, RecN forms a single focus per nucleoid PubMed

Database entries

• Structure:

• UniProt: P17894

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: ahrC-recN PubMed

• Expression browser: recN PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:
  • 1A891 ( recN::cat), PubMed, available at BGSC

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Peter Graumann, Freiburg University, Germany homepage

References

Reviews

Additional reviews: PubMed

Silvia Ayora, Begoña Carrasco, Paula P Cárdenas, Carolina E César, Cristina Cañas, Tribhuwan Yadav, Chiara Marchisone, Juan C Alonso
Double-strand break repair in bacteria: a view from Bacillus subtilis.
FEMS Microbiol Rev: 2011, 35(6);1055-81
[PubMed:21517913] [WorldCat.org] [DOI] (I p)

Peter L Graumann, Tobias Knust
Dynamics of the bacterial SMC complex and SMC-like proteins involved in DNA repair.
Chromosome Res: 2009, 17(2);265-75
[PubMed:19308706] [WorldCat.org] [DOI] (I p)

Original publications

Additional publications: PubMed