YvgN

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  • Description: glyoxal reductase, general stress protein

Gene name yvgN
Synonyms yvsB
Essential no
Product glyoxal reductase
Function unknown
Gene expression levels in SubtiExpress: yvgN
MW, pI 31 kDa, 5.066
Gene length, protein length 828 bp, 276 aa
Immediate neighbours yvgM, yvgO
Sequences Protein DNA Advanced_DNA
Genetic context
YvgN context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YvgN expression.png
























Categories containing this gene/protein

general stress proteins (controlled by SigB), resistance against oxidative and electrophile stress

This gene is a member of the following regulons

SigB regulon, SinR regulon

The gene

Basic information

  • Locus tag: BSU33400

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Lactaldehyde + NADP+ = methylglyoxal + NADPH (according to Swiss-Prot)
  • Protein family: aldo/keto reductase family (according to Swiss-Prot)
  • Paralogous protein(s): YtbE

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Jian Lei, Yan-Feng Zhou, Lan-Fen Li, Xiao-Dong Su
Structural and biochemical analyses of YvgN and YtbE from Bacillus subtilis.
Protein Sci: 2009, 18(8);1792-800
[PubMed:19585557] [WorldCat.org] [DOI] (I p)

Frances Chu, Daniel B Kearns, Steven S Branda, Roberto Kolter, Richard Losick
Targets of the master regulator of biofilm formation in Bacillus subtilis.
Mol Microbiol: 2006, 59(4);1216-28
[PubMed:16430695] [WorldCat.org] [DOI] (P p)

A Sakai, K Katayama, T Katsuragi, Y Tani
Glycolaldehyde-forming route in Bacillus subtilis in relation to vitamin B6 biosynthesis.
J Biosci Bioeng: 2001, 91(2);147-52
[PubMed:16232966] [WorldCat.org] [DOI] (P p)

Dirk Höper, Uwe Völker, Michael Hecker
Comprehensive characterization of the contribution of individual SigB-dependent general stress genes to stress resistance of Bacillus subtilis.
J Bacteriol: 2005, 187(8);2810-26
[PubMed:15805528] [WorldCat.org] [DOI] (P p)