LytG

• Description: similar to N-acetylmuramoyl-L-alanine amidase
  
  

Gene name	lytG
Synonyms	yubE
Essential	no
Product	unknown
Function	cell wall turnover
Gene expression levels in SubtiExpress: lytG
MW, pI	31 kDa, 8.277
Gene length, protein length	846 bp, 282 aa
Immediate neighbours	yubF, yubD
Sequences	Protein DNA Advanced_DNA
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

cell wall degradation/ turnover

The gene

Basic information

• Locus tag: BSU31120

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Hydrolysis of 1,4-beta-linkages between N-acetyl-D-glucosamine and N-acetylmuramic acid residues in a peptidoglycan (according to Swiss-Prot)

• Protein family: glycosyl hydrolase 73 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • secreted (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O32083

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: lytG PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Fusinita van den Ent, Mark Leaver, Felipe Bendezu, Jeff Errington, Piet de Boer, Jan Löwe
Dimeric structure of the cell shape protein MreC and its functional implications.
Mol Microbiol: 2006, 62(6);1631-42
[PubMed:17427287] [WorldCat.org] [DOI] (P p)

Gavin J Horsburgh, Abdelmadjid Atrih, Michael P Williamson, Simon J Foster
LytG of Bacillus subtilis is a novel peptidoglycan hydrolase: the major active glucosaminidase.
Biochemistry: 2003, 42(2);257-64
[PubMed:12525152] [WorldCat.org] [DOI] (P p)