YtrE

• Description: ABC transporter (ATP-binding protein)
  
  

Gene name	ytrE
Synonyms
Essential	no
Product	ABC transporter (ATP-binding protein)
Function	unknown
Gene expression levels in SubtiExpress: ytrE
Interactions involving this protein in SubtInteract: YtrE
Metabolic function and regulation of this protein in SubtiPathways: Central C-metabolism
MW, pI	25 kDa, 5.98
Gene length, protein length	693 bp, 231 aa
Immediate neighbours	ytrF, ytrD
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ABC transporters, cold stress proteins, membrane proteins

This gene is a member of the following regulons

YtrA regulon

The gene

Basic information

• Locus tag: BSU30420

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: ABC transporter family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • (YtrB-YtrE)-(YtrC-YtrD)-YtrF PubMed

• Localization: cell membrane (via YtrC-YtrD) PubMed

Database entries

• Structure:

• UniProt: O34392

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: ytrG-ytrA-ytrB-ytrC-ytrD-ytrE-ytrF PubMed

• Expression browser: ytrE PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • induced by ramoplanin (YtrA) PubMed
  • expressed early in the stationary phase PubMed
  • induced by cold shock (6-fold) PubMed
  • induced by antibiotics interfering with membrane-bound steps of cell wall biosynthesis PubMed

• Regulatory mechanism:
  • YtrA: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed

Michaela Wenzel, Bastian Kohl, Daniela Münch, Nadja Raatschen, H Bauke Albada, Leendert Hamoen, Nils Metzler-Nolte, Hans-Georg Sahl, Julia E Bandow
Proteomic response of Bacillus subtilis to lantibiotics reflects differences in interaction with the cytoplasmic membrane.
Antimicrob Agents Chemother: 2012, 56(11);5749-57
[PubMed:22926563] [WorldCat.org] [DOI] (I p)

Carsten L Beckering, Leif Steil, Michael H W Weber, Uwe Völker, Mohamed A Marahiel
Genomewide transcriptional analysis of the cold shock response in Bacillus subtilis.
J Bacteriol: 2002, 184(22);6395-402
[PubMed:12399512] [WorldCat.org] [DOI] (P p)

K I Yoshida, Y Fujita, S D Ehrlich
An operon for a putative ATP-binding cassette transport system involved in acetoin utilization of Bacillus subtilis.
J Bacteriol: 2000, 182(19);5454-61
[PubMed:10986249] [WorldCat.org] [DOI] (P p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)