RecJ

• Description: single-strand DNA-specific exonuclease
  
  

Gene name	yrvE
Synonyms	recJ
Essential	no
Product	single-strand DNA-specific exonuclease
Function	unknown
Gene expression levels in SubtiExpress: yrvE
Interactions involving this protein in SubtInteract: YrvE
Metabolic function and regulation of this protein in SubtiPathways: Nucleotides (regulation)
MW, pI	87 kDa, 5.181
Gene length, protein length	2358 bp, 786 aa
Immediate neighbours	apt, yrvD
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

DNA repair/ recombination

This gene is a member of the following regulons

stringent response, Efp-dependent proteins

The gene

Basic information

• Locus tag: BSU27620

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: recJ family (according to Swiss-Prot)

• Paralogous protein(s): YorK

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • SsbA-YrvE PubMed

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O32044

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: yrvE-apt PubMed

• Expression browser: yrvE PubMed

• Sigma factor:

• Regulation:
  • RelA dependent downregulation (Class I) during stringent response PubMed

• Regulatory mechanism:

• Additional information:
  • translation is likely to require Efp due to the presence of several consecutive proline residues PubMed

Biological materials

• Mutant:
  • GP895 (recJ::kan), available in Stülke lab

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed