YqeL

• Description: ribosomal silencing factor
  
  

Gene name	yqeL
Synonyms
Essential	no
Product	ribosomal silencing factor
Function	translation
Gene expression levels in SubtiExpress: yqeL
MW, pI	13 kDa, 4.367
Gene length, protein length	354 bp, 118 aa
Immediate neighbours	yqeM, yqeK
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

translation

The gene

Basic information

• Locus tag: BSU25620

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:
  • silences translation by binding to the L14 protein of the large ribosomal subunit and, as a consequence, impairs subunit joining PubMed

• Protein family: Iojap family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • RplN-YqeL PubMed, the interaction serves to silence translation PubMed

• Localization:

Database entries

• Structure:

• UniProt: P54457

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: yqeL PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Roman Häuser, Markus Pech, Jaroslaw Kijek, Hiroshi Yamamoto, Björn Titz, Florian Naeve, Andrey Tovchigrechko, Kaori Yamamoto, Witold Szaflarski, Nono Takeuchi, Thorsten Stellberger, Markus E Diefenbacher, Knud H Nierhaus, Peter Uetz
RsfA (YbeB) proteins are conserved ribosomal silencing factors.
PLoS Genet: 2012, 8(7);e1002815
[PubMed:22829778] [WorldCat.org] [DOI] (I p)