GcvPB
Revision as of 13:16, 13 May 2013 by 134.76.70.252 (talk)
- Description: glycine decarboxylase (subunit 2)
Gene name | gcvPB |
Synonyms | yqhK, gcvP |
Essential | no |
Product | glycine decarboxylase (subunit 2) |
Function | glycine utilization |
Gene expression levels in SubtiExpress: gcvPB | |
MW, pI | 54 kDa, 5.283 |
Gene length, protein length | 1464 bp, 488 aa |
Immediate neighbours | yqhL, gcvPA |
Sequences | Protein DNA Advanced_DNA |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
utilization of amino acids, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU24550
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Glycine + H-protein-lipoyllysine = H-protein-S-aminomethyldihydrolipoyllysine + CO2 (according to Swiss-Prot)
- Protein family: C-terminal subunit subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P54377
- KEGG entry: [3]
- E.C. number: 1.4.4.2
Additional information
Expression and regulation
- Sigma factor:
- Regulatory mechanism:
- induction requires a co-operatively acting riboswitch (Gly-box) PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Maumita Mandal, Mark Lee, Jeffrey E Barrick, Zasha Weinberg, Gail Mitchell Emilsson, Walter L Ruzzo, Ronald R Breaker
A glycine-dependent riboswitch that uses cooperative binding to control gene expression.
Science: 2004, 306(5694);275-9
[PubMed:15472076]
[WorldCat.org]
[DOI]
(I p)
Ulrike Mäder, Georg Homuth, Christian Scharf, Knut Büttner, Rüdiger Bode, Michael Hecker
Transcriptome and proteome analysis of Bacillus subtilis gene expression modulated by amino acid availability.
J Bacteriol: 2002, 184(15);4288-95
[PubMed:12107147]
[WorldCat.org]
[DOI]
(P p)