YvcA

• Description: required for complex colony development
  
  

Gene name	yvcA
Synonyms
Essential	no
Product	lipoprotein
Function	complex colony development
Gene expression levels in SubtiExpress: yvcA
MW, pI	27 kDa, 6.834
Gene length, protein length	723 bp, 241 aa
Immediate neighbours	yvcB, hisI
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

biofilm formation, membrane proteins

This gene is a member of the following regulons

AbrB regulon, DegU regulon

The gene

Basic information

• Locus tag: BSU34850

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O06965

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: yvcA–yvcB–yvzA PubMed

• Expression browser: yvcA PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:
  • DegU-P: transcription activation PubMed
  • AbrB: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Daniel T Verhamme, Ewan J Murray, Nicola R Stanley-Wall
DegU and Spo0A jointly control transcription of two loci required for complex colony development by Bacillus subtilis.
J Bacteriol: 2009, 191(1);100-8
[PubMed:18978066] [WorldCat.org] [DOI] (I p)

Daniël T Verhamme, Taryn B Kiley, Nicola R Stanley-Wall
DegU co-ordinates multicellular behaviour exhibited by Bacillus subtilis.
Mol Microbiol: 2007, 65(2);554-68
[PubMed:17590234] [WorldCat.org] [DOI] (P p)