CatR

From SubtiWiki
Revision as of 15:58, 7 August 2012 by 134.76.70.252 (talk)
Jump to: navigation, search
Gene name catR
Synonyms yvaP
Essential no
Product MarR/DUF24 family transcription repressor
Function resistance against oxidative and electrophile stress
Gene expression levels in SubtiExpress: catR
MW, pI 26 kDa, 9.887
Gene length, protein length 708 bp, 236 aa
Immediate neighbours yvaO, yvaQ
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YvaP context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
CatR expression.png
























Categories containing this gene/protein

transcription factors and their control, resistance against oxidative and electrophile stress

This gene is a member of the following regulons

The CatR regulon:

catD-catE

The gene

Basic information

  • Locus tag: BSU33680

Phenotypes of a mutant

increased resistance to catechol and quinones PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Paralogous protein(s): YodB

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: in responsse to the presence of diamides or quinones, Cys-7 forms intermolecular disulfide bonds, this results in loss of DNA-bindig ability (induction of catD-catE) PubMed
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Haike Antelmann,University of Greifswald, Germany

Your additional remarks

References

Reviews

Antelmann H, Helmann JD.
Thiol-based redox switches and gene regulation.
Antioxid Redox Signal. 2011,14:1049-63.
PubMed


Original Articles