OxdC

• Description: oxalate decarboxylase
  
  

Gene name	oxdC
Synonyms	yvrK
Essential	no
Product	oxalate decarboxylase
Function	unknown
MW, pI	43 kDa, 5.101
Gene length, protein length	1155 bp, 385 aa
Immediate neighbours	yvrJ, yvrL
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

acid stress proteins (controlled by YvrI-YvrHa), phosphoproteins

This gene is a member of the following regulons

YvrI-YvrHa regulon

The gene

Basic information

• Locus tag: BSU33240

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Oxalate = formate + CO₂ (according to Swiss-Prot)

• Protein family:

• Paralogous protein(s): OxdD

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:
  • phosphorylated on Arg-12 PubMed

• Cofactor(s): requires Mn(II) for activity PubMed

• Effectors of protein activity:

• Interactions:

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• Structure: 1UW8

• UniProt: O34714

• KEGG entry: [2]

• E.C. number: 4.1.1.2

Expression and regulation

• Operon: oxdC-yvrL PubMed

• Expression browser: oxdC PubMed

• Sigma factor: YvrI-YvrHa PubMed

• Regulation: induced by acidic growth conditions PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

John Helmann, Cornell University, USA Homepage

References

Reviews

Miia R Mäkelä, Kristiina Hildén, Taina K Lundell
Oxalate decarboxylase: biotechnological update and prevalence of the enzyme in filamentous fungi.
Appl Microbiol Biotechnol: 2010, 87(3);801-14
[PubMed:20464388] [WorldCat.org] [DOI] (I p)

Original publications

Additional publications: PubMed