RplT

• Description: ribosomal protein
  
  

Gene name	rplT
Synonyms
Essential	yes PubMed
Product	ribosomal protein L20
Function	translation
Gene expression levels in SubtiExpress: rplT
Interactions involving this protein in SubtInteract: RplT
MW, pI	13 kDa, 11.901
Gene length, protein length	357 bp, 119 aa
Immediate neighbours	ysdA, rpmI
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

translation, RNA binding regulators, essential genes, membrane proteins

This gene is a member of the following regulons

RplT regulon, stringent response

The gene

Basic information

• Locus tag: BSU28850

Phenotypes of a mutant

essential PubMed

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: ribosomal protein L20P family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P55873

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: infC-rpmI-rplT-ysdA PubMed

• Expression browser: rplT PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • RelA dependent downregulation (Class I) during stringent response PubMed

• Regulatory mechanism:
  • binding of RplT to a RNA switch in the infC leader region causes transcription termination PubMed

• Additional information:
  • expression of IF3 is uncoupled from that of L35 and L20 by RNase Y-dependent processing PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: