YhcR

Gene name	yhcR
Synonyms
Essential	no
Product	extracellular non-specific endonuclease, Rnase
Function	utilization of nucleic acids
Gene expression levels in SubtiExpress: yhcR
Interactions involving this protein in SubtInteract: YhcR
MW, pI	132 kDa, 4.693
Gene length, protein length	3651 bp, 1217 aa
Immediate neighbours	yhcQ, yhcS
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

biosynthesis/ acquisition of nucleotides, Rnases

The gene

Basic information

• Locus tag: BSU09190

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s): YfkN

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: YhcS-YhcR PubMed (anchoring to the cell wall)

• Localization: extracellular (signal peptide) PubMed, attached to the cell wall PubMed

Database entries

• Structure:

• UniProt: P54602

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: yhcR PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

David Bechhofer, Mount Sinai School, New York, USA Homepage

References

Additional referencecs: PubMed

Hamidreza Fasehee, Helga Westers, Albert Bolhuis, Haike Antelmann, Michael Hecker, Wim J Quax, Agha F Mirlohi, Jan Maareten van Dijl, Gholamreza Ahmadian
Functional analysis of the sortase YhcS in Bacillus subtilis.
Proteomics: 2011, 11(19);3905-13
[PubMed:21800427] [WorldCat.org] [DOI] (I p)

Birgit Voigt, Haike Antelmann, Dirk Albrecht, Armin Ehrenreich, Karl-Heinz Maurer, Stefan Evers, Gerhard Gottschalk, Jan Maarten van Dijl, Thomas Schweder, Michael Hecker
Cell physiology and protein secretion of Bacillus licheniformis compared to Bacillus subtilis.
J Mol Microbiol Biotechnol: 2009, 16(1-2);53-68
[PubMed:18957862] [WorldCat.org] [DOI] (I p)

Irina A Oussenko, Roberto Sanchez, David H Bechhofer
Bacillus subtilis YhcR, a high-molecular-weight, nonspecific endonuclease with a unique domain structure.
J Bacteriol: 2004, 186(16);5376-83
[PubMed:15292138] [WorldCat.org] [DOI] (P p)