GltR

From SubtiWiki
Revision as of 12:07, 16 April 2012 by 134.76.70.252 (talk)
Jump to: navigation, search
Gene name gltR
Synonyms yrdL
Essential no
Product transcriptional regulator (LysR family)
Function unknown
MW, pI 32 kDa, 6.653
Gene length, protein length 888 bp, 296 aa
Immediate neighbours yrdN, yrdK
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
GltR context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

transcription factors and their control

This gene is a member of the following regulons

GltR regulon

The GltR regulon:

The gene

Basic information

  • Locus tag: BSU26670

Phenotypes of a mutant

The function of this protein is unknown. However, certain mutant forms are able to activate expression of the gltA-gltB operon (and thus to replace the cognate activator protein GltC)

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

The function of this protein is unknown. However, certain mutant forms are able to activate expression of the gltA-gltB operon (and thus to replace the cognate activator protein GltC)

Expression and regulation

  • Operon: gltR (according to DBTBS)
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant: GP345 (erm), available in the Stülke lab
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Linc Sonenshein, Tufts University, Boston, MA, USA Homepage

Your additional remarks

References

B R Belitsky, A L Sonenshein
Altered transcription activation specificity of a mutant form of Bacillus subtilis GltR, a LysR family member.
J Bacteriol: 1997, 179(4);1035-43
[PubMed:9023181] [WorldCat.org] [DOI] (P p)