MurR

• Description: probably transcriptional regulator of genes required for the utilization of N-acetylmuramic acid, homolog to E. coli MurR
  
  

Gene name	murR
Synonyms	ybbH
Essential	no
Product	transcriptional repressor
Function	probably regulation of muramic acid utilization
Metabolic function and regulation of this protein in SubtiPathways: Murein recycling
MW, pI	30 kDa, 6.873
Gene length, protein length	849 bp, 283 aa
Immediate neighbours	murP, murQ
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

cell wall degradation/ turnover, utilization of specific carbon sources, transcription factors and their control

The gene

Basic information

• Locus tag: BSU01690

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 2O3F (N-terminal domain)

• UniProt: Q45581

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: murR PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Silke Litzinger, Amanda Duckworth, Katja Nitzsche, Christian Risinger, Valentin Wittmann, Christoph Mayer
Muropeptide rescue in Bacillus subtilis involves sequential hydrolysis by beta-N-acetylglucosaminidase and N-acetylmuramyl-L-alanine amidase.
J Bacteriol: 2010, 192(12);3132-43
[PubMed:20400549] [WorldCat.org] [DOI] (I p)

Ulrike Dahl, Tina Jaeger, Bao Trâm Nguyen, Julia M Sattler, Christoph Mayer
Identification of a phosphotransferase system of Escherichia coli required for growth on N-acetylmuramic acid.
J Bacteriol: 2004, 186(8);2385-92
[PubMed:15060041] [WorldCat.org] [DOI] (P p)

Jonathan Reizer, Steffi Bachem, Aiala Reizer, Maryvonne Arnaud, Milton H Saier, Jörg Stülke
Novel phosphotransferase system genes revealed by genome analysis - the complete complement of PTS proteins encoded within the genome of Bacillus subtilis.
Microbiology (Reading): 1999, 145 ( Pt 12);3419-3429
[PubMed:10627040] [WorldCat.org] [DOI] (P p)