YqaM

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  • Description: similar to phage-related protein, skin-element

Gene name yqaM
Synonyms
Essential no
Product unknown
Function unknown
Interactions involving this protein in SubtInteract: YqaM
MW, pI 35 kDa, 5.386
Gene length, protein length 939 bp, 313 aa
Immediate neighbours yqaN, yqaL
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YqaM context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

Skin element

This gene is a member of the following regulons

SknR regulon

The gene

Basic information

  • Locus tag: BSU26260

Phenotypes of a mutant

  • overexpression of YqaM causes cell filamentation and abnormal chromosome segregation PubMed
  • overexpression of YqaM inhibits initiation DNA replication, perhaps due to the interaction with DnaC PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s): XkdC

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • not expressed during normal growth (SknR) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Tatsu Kimura, Yukie Amaya, Kazuo Kobayashi, Naotake Ogasawara, Tsutomu Sato
Repression of sigK intervening (skin) element gene expression by the CI-like protein SknR and effect of SknR depletion on growth of Bacillus subtilis cells.
J Bacteriol: 2010, 192(23);6209-16
[PubMed:20889742] [WorldCat.org] [DOI] (I p)

Jean-Christophe Meile, Ling Juan Wu, S Dusko Ehrlich, Jeff Errington, Philippe Noirot
Systematic localisation of proteins fused to the green fluorescent protein in Bacillus subtilis: identification of new proteins at the DNA replication factory.
Proteomics: 2006, 6(7);2135-46
[PubMed:16479537] [WorldCat.org] [DOI] (P p)

Marie-Françoise Noirot-Gros, Etienne Dervyn, Ling Juan Wu, Peggy Mervelet, Jeffery Errington, S Dusko Ehrlich, Philippe Noirot
An expanded view of bacterial DNA replication.
Proc Natl Acad Sci U S A: 2002, 99(12);8342-7
[PubMed:12060778] [WorldCat.org] [DOI] (P p)