NadR

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  • Description: transcriptional repressor of genes involved in NAD biosynthesis

Gene name nadR
Synonyms yrxA
Essential no
Product transcriptional repressor
Function regulation of NAD biosynthesis
MW, pI 19 kDa, 5.759
Gene length, protein length 534 bp, 178 aa
Immediate neighbours nifS, pheA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YrxA context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

biosynthesis of cofactors, transcription factors and their control

This gene is a member of the following regulons

NadR regulon

The NadR regulon:

The gene

Basic information

  • Locus tag: BSU27890

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed in the presence of nicotinic acid (NadR) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Alessandra Albertini, University of Pavia, Italy homepage

Your additional remarks

References