KamA

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  • Description: lysine 2,3-aminomutase

Gene name kamA
Synonyms yodO
Essential no
Product lysine 2,3-aminomutase
Function unknown
MW, pI 53 kDa, 6.04
Gene length, protein length 1413 bp, 471 aa
Immediate neighbours yozE, yodP
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
KamA context.gif
This image was kindly provided by SubtiList




Categories containing this gene/protein

poorly characterized/ putative enzymes

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU19690

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: L-lysine = beta-lysine
  • Protein family: UPF0720 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Stefan Müller, Tamara Hoffmann, Helena Santos, Stephan H Saum, Erhard Bremer, Volker Müller
Bacterial abl-like genes: production of the archaeal osmolyte N(ε)-acetyl-β-lysine by homologous overexpression of the yodP-kamA genes in Bacillus subtilis.
Appl Microbiol Biotechnol: 2011, 91(3);689-97
[PubMed:21538109] [WorldCat.org] [DOI] (I p)

D Chen, F J Ruzicka, P A Frey
A novel lysine 2,3-aminomutase encoded by the yodO gene of bacillus subtilis: characterization and the observation of organic radical intermediates.
Biochem J: 2000, 348 Pt 3(Pt 3);539-49
[PubMed:10839984] [WorldCat.org] (P p)