LmrA

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Gene name lmrA
Synonyms lin-2, yccB
Essential no
Product transcriptional regulator
Function regulation of lincomycin resistance
MW, pI 20 kDa, 5.033
Gene length, protein length 564 bp, 188 aa
Immediate neighbours lmrB, ansZ
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
LmrA context.gif
This image was kindly provided by SubtiList




Categories containing this gene/protein

transcription factors and their control, resistance against toxins/ antibiotics

This gene is a member of the following regulons

LmrA regulon

The gene

Basic information

  • Locus tag: BSU02680

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s): YxaF

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity: flavonoids such as quercetin serve as inducers, binding results in release from DNA PubMed
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • induced by flavonoids such as quercetin (LmrA)PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References