YrpC

• Description: glutamate racemase
  
  

Gene name	yrpC
Synonyms
Essential	no
Product	glutamate racemase
Function	peptidoglycan precursor biosynthesis
Metabolic function and regulation of this protein in SubtiPathways: Cell wall
MW, pI	29 kDa, 6.74
Gene length, protein length	795 bp, 265 aa
Immediate neighbours	yrpB, yrpD
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU26810

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

Categories containing this gene/protein

cell wall synthesis, biosynthesis of cell wall components

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: L-glutamate = D-glutamate (according to Swiss-Prot)

• Protein family: aspartate/glutamate racemases family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 2JFN (from Escherichia coli, 36% identity, 54% similarity) PubMed

• UniProt: O05412

• KEGG entry: [2]

• E.C. number: 5.1.1.3

Expression and regulation

• Operon:

• Sigma factor:

• Regulation: expressed only in minimal medium, not in complex medium PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Keitarou Kimura, Lam-Son Phan Tran, Yoshifumi Itoh
Roles and regulation of the glutamate racemase isogenes, racE and yrpC, in Bacillus subtilis.
Microbiology (Reading): 2004, 150(Pt 9);2911-2920
[PubMed:15347750] [WorldCat.org] [DOI] (P p)