TcyP

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  • Description: cystine transporter, membrane protein

Gene name tcyP
Synonyms yhcL
Essential no
Product cystine transporter, membrane protein
Function cystine uptake
Metabolic function and regulation of this protein in SubtiPathways:
Ammonium/ glutamate
MW, pI 48 kDa, 9.471
Gene length, protein length 1389 bp, 463 aa
Immediate neighbours yhcK, yhcM
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YhcL context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU09130

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

Categories containing this gene/protein

transporters/ other, biosynthesis/ acquisition of amino acids, membrane proteins

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: cystine-proton symporter PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information: K(m) = 0.6 myM PubMed
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: membrane associated PubMed

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: tcyP
  • Regulation:
    • repressed in the presence of sulfate or cysteine (CymR) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Isabelle Martin-Verstraete, Institute Pasteur, Paris, France

Your additional remarks

References