YwcE

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  • Description: holin, required for spore morphogenesis and germination

Gene name ywcE
Synonyms ipa-41r
Essential no
Product holin
Function required for spore morphogenesis and germination
MW, pI 9 kDa, 9.845
Gene length, protein length 261 bp, 87 aa
Immediate neighbours rodA, qoxD
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YwcE context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU38130

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: ywcE family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed during the log phase (AbrB), expressed only at the onset of stationary phase PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Gonçalo Real, Sérgio M Pinto, Ghislain Schyns, Teresa Costa, Adriano O Henriques, Charles P Moran
A gene encoding a holin-like protein involved in spore morphogenesis and spore germination in Bacillus subtilis.
J Bacteriol: 2005, 187(18);6443-53
[PubMed:16159778] [WorldCat.org] [DOI] (P p)

E Presecan, I Moszer, L Boursier, H Cruz Ramos, V de la Fuente, M-F Hullo, C Lelong, S Schleich, A Sekowska, B H Song, G Villani, F Kunst, A Danchin, P Glaser
The Bacillus subtilis genome from gerBC (311 degrees) to licR (334 degrees).
Microbiology (Reading): 1997, 143 ( Pt 10);3313-3328
[PubMed:9353933] [WorldCat.org] [DOI] (P p)