LonA
- Description: class III heat-shock ATP-dependent protease
Gene name | lonA |
Synonyms | lon |
Essential | no |
Product | class III heat-shock ATP-dependent protease |
Function | protein quality control |
Regulation of this protein in SubtiPathways: Stress | |
MW, pI | 86 kDa, 5.774 |
Gene length, protein length | 2322 bp, 774 aa |
Immediate neighbours | ysxC, lonB |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU28200
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
A mutation in lonA suppresses the motility defect of a lytC mutant PubMed
Evidence for a specific DNA binding activitity of the α-domain was found PubMed
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Hydrolysis of proteins in presence of ATP (according to Swiss-Prot)
- Protein family: peptidase S16 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions: homohexameric protein PubMed
- Localization: coincident with the nucleoid during normal growth and localized to the forespore during development PubMed
Database entries
- Structure: 1X37 (Ssd domain)
- UniProt: P37945
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References