FtsX

• Description: ABC transporter (membrane protein) (FtsE-FtsX), required for proper activation of Spo0A and initiation of sporulation
  
  

Gene name	ftsX
Synonyms
Essential	no
Product	ABC transporter (membrane protein)
Function	initiation of sporulation
MW, pI	32 kDa, 10.016
Gene length, protein length	888 bp, 296 aa
Immediate neighbours	ctpB, ftsE
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU35250

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: FtsX subfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: FtsE-FtsX PubMed

• Localization: cell membrane (according to Swiss-Prot), membrane associated PubMed

Database entries

• Structure:

• UniProt: O34876

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: ftsE-ftsX (according to DBTBS)

• Sigma factor:

• Regulation:
  • repressed under conditions that trigger sporulation (Spo0A) PubMed

• Regulatory mechanism:
  • Spo0A: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: