YvgN

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  • Description: glyoxal reductase, general stress protein

Gene name yvgN
Synonyms yvsB
Essential no
Product glyoxal reductase
Function unknown
MW, pI 31 kDa, 5.066
Gene length, protein length 828 bp, 276 aa
Immediate neighbours yvgM, yvgO
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YvgN context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU33400

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

Categories containing this gene/protein

general stress proteins (controlled by SigB), resistance against oxidative and electrophile stress

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Lactaldehyde + NADP+ = methylglyoxal + NADPH (according to Swiss-Prot)
  • Protein family: aldo/keto reductase family (according to Swiss-Prot)
  • Paralogous protein(s): YtbE

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Jian Lei, Yan-Feng Zhou, Lan-Fen Li, Xiao-Dong Su
Structural and biochemical analyses of YvgN and YtbE from Bacillus subtilis.
Protein Sci: 2009, 18(8);1792-800
[PubMed:19585557] [WorldCat.org] [DOI] (I p)

Frances Chu, Daniel B Kearns, Steven S Branda, Roberto Kolter, Richard Losick
Targets of the master regulator of biofilm formation in Bacillus subtilis.
Mol Microbiol: 2006, 59(4);1216-28
[PubMed:16430695] [WorldCat.org] [DOI] (P p)

A Sakai, K Katayama, T Katsuragi, Y Tani
Glycolaldehyde-forming route in Bacillus subtilis in relation to vitamin B6 biosynthesis.
J Biosci Bioeng: 2001, 91(2);147-52
[PubMed:16232966] [WorldCat.org] [DOI] (P p)

Dirk Höper, Uwe Völker, Michael Hecker
Comprehensive characterization of the contribution of individual SigB-dependent general stress genes to stress resistance of Bacillus subtilis.
J Bacteriol: 2005, 187(8);2810-26
[PubMed:15805528] [WorldCat.org] [DOI] (P p)