BglS

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  • Description: endo-beta-1,3-1,4 glucanase

Gene name bglS
Synonyms bgl, licS
Essential no
Product endo-beta-1,3-1,4 glucanase
Function lichenan degradation
Metabolic function and regulation of this protein in SubtiPathways:
Sugar catabolism
MW, pI 27 kDa, 6.482
Gene length, protein length 726 bp, 242 aa
Immediate neighbours citH, licT
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
BglS context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU39070

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Hydrolysis of (1->4)-beta-D-glucosidic linkages in beta-D-glucans containing (1->3)- and (1->4)-bonds (according to Swiss-Prot)
  • Protein family: glycosyl hydrolase 16 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: extracellular (signal peptide) PubMed

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • repressed by glucose (3.1-fold) (CcpA) PubMed
    • expressed in the stationary phase (temporal activation) PubMed
    • weak induction by ß-glucosides (LicT) PubMed
  • Additional information:

Biological materials

  • Mutant: GP427 (licT-bglS, erm), BGW7 (cat), both available in the Stülke lab
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References