YtcG

• Description: putative negative regulator of transcription of ribonucleotide reductase nrd genes and operons
  
  

Gene name	ytcG
Synonyms	nrdR
Essential	no
Product	putative regulator protein
Function	unknown
MW, pI	17 kDa, 8.05
Gene length, protein length	456 bp, 152 aa
Immediate neighbours	dnaB, speD
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU29000

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: nrdR family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: Q45549

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: ytcG PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Inna Grinberg, Tanya Shteinberg, Batia Gorovitz, Yair Aharonowitz, Gerald Cohen, Ilya Borovok
The Streptomyces NrdR transcriptional regulator is a Zn ribbon/ATP cone protein that binds to the promoter regions of class Ia and class II ribonucleotide reductase operons.
J Bacteriol: 2006, 188(21);7635-44
[PubMed:16950922] [WorldCat.org] [DOI] (P p)

Alia Lapidus, Nathalie Galleron, Alexei Sorokin, S Dusko Ehrlich
Sequencing and functional annotation of the Bacillus subtilis genes in the 200 kb rrnB-dnaB region.
Microbiology (Reading): 1997, 143 ( Pt 11);3431-3441
[PubMed:9387221] [WorldCat.org] [DOI] (P p)