IspC

• Description: 1-deoxy-D-xylulose-5-phosphate reductoisomerase
  
  

Gene name	ispC
Synonyms	yluB, dxr
Essential	yes PubMed
Product	1-deoxy-D-xylulose-5-phosphate reductoisomerase
Function	biosynthesis of steroids
MW, pI	43 kDa, 5.801
Gene length, protein length	1164 bp, 388 aa
Immediate neighbours	cdsA, rasP
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU16550

Phenotypes of a mutant

essential PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: 2-C-methyl-D-erythritol 4-phosphate + NADP⁺ = 1-deoxy-D-xylulose 5-phosphate + NADPH (according to Swiss-Prot)

• Protein family: DXR family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O31753

• KEGG entry: [2]

• E.C. number: 1.1.1.267

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: