Difference between revisions of "PyrK"

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<pubmed>8206849,8759868,1709162,10545205, </pubmed>
# Author1, Author2 & Author3 (year) Title ''Journal'' '''volume:''' page-page. [http://www.ncbi.nlm.nih.gov/sites/entrez/PMID PubMed]
 

Revision as of 01:32, 16 June 2009

  • Description: dihydoorotic acid dehydrogenase (electron transfer subunit)

Gene name pyrK
Synonyms pyrDII, ylxD
Essential no
Product dihydoorotic acid dehydrogenase (electron transfer subunit)
Function pyrimidine biosynthesis
MW, pI 27 kDa, 5.582
Gene length, protein length 768 bp, 256 aa
Immediate neighbours pyrAB, pyrD
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PyrK context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU15530

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: FAD-binding FR-type domain (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • induced in the absence of uridine nucleotides (PyrR) PubMed
  • Regulatory mechanism:
    • PyrR: RNA switch, transcription termination/ antitermination (in the presence of uridine nucleotides: termination, in their absence: antitermination) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References