Difference between revisions of "CdsA"

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Revision as of 13:02, 15 June 2009

  • Description: phosphatidate cytidylyltransferase

Gene name cdsA
Synonyms
Essential yes PubMed
Product phosphatidate cytidylyltransferase
Function biosynthesis of phospholipids
MW, pI 30 kDa, 7.866
Gene length, protein length 807 bp, 269 aa
Immediate neighbours uppS, ispC
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
CdsA context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU16540

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: CTP + phosphatidate = diphosphate + CDP-diacylglycerol (according to Swiss-Prot)
  • Protein family: CDS family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information: the mRNA is very stable (half-life > 15 min) PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

G Hambraeus, C von Wachenfeldt, L Hederstedt
Genome-wide survey of mRNA half-lives in Bacillus subtilis identifies extremely stable mRNAs.
Mol Genet Genomics: 2003, 269(5);706-14
[PubMed:12884008] [WorldCat.org] [DOI] (P p)