CydC

• Description: ABC transporter required for expression of cytochrome bd (ATP-binding protein)
  
  

Gene name	cydC
Synonyms	yxkM
Essential	no
Product	ABC transporter (ATP-binding protein)
Function	required for expression of cytochrome bd
MW, pI	62 kDa, 8.511
Gene length, protein length	1701 bp, 567 aa
Immediate neighbours	cydD, cydB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU38740

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• Swiss prot entry: P94366

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: cydA-cydB-cydC-cydD PubMed

• Sigma factor:

• Regulation:
  • repressed by glucose (CcpA)
  • induced under anaerobic conditions (Rex) PubMed
  • expressed under anaerobic conditions (ResD) PubMed

• Regulatory mechanism:
  • CcpA: transcription repression
  • Rex: transcription repression PubMed
  • ResD: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Ankita Puri-Taneja, Matthew Schau, Yinghua Chen, F Marion Hulett
Regulators of the Bacillus subtilis cydABCD operon: identification of a negative regulator, CcpA, and a positive regulator, ResD.
J Bacteriol: 2007, 189(9);3348-58
[PubMed:17322317] [WorldCat.org] [DOI] (P p)

Matthew Schau, Yinghua Chen, F Marion Hulett
Bacillus subtilis YdiH is a direct negative regulator of the cydABCD operon.
J Bacteriol: 2004, 186(14);4585-95
[PubMed:15231791] [WorldCat.org] [DOI] (P p)

1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed