Difference between revisions of "ParA"

From SubtiWiki
Jump to: navigation, search
Line 93: Line 93:
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
 +
** repressed under conditions that trigger sporulation ([[Spo0A]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/14651647 PubMed]
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 +
** [[Spo0A]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/14651647 PubMed]
  
 
* '''Additional information:'''  
 
* '''Additional information:'''  

Revision as of 17:38, 11 June 2009

  • Description: centromere-like function involved in forespore chromosome partitioning / negative regulation of sporulation initiation

Gene name soj
Synonyms spo0JA
Essential no
Product negative regulator of sporulation initiation
Function forespore chromosome partitioning / negative regulation of sporulation initiation
MW, pI 27 kDa, 4.903
Gene length, protein length 759 bp, 253 aa
Immediate neighbours spo0J, yyaB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
Soj context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU40970

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: parA family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
    • repressed under conditions that trigger sporulation (Spo0A) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Stephan Gruber, Jeff Errington
Recruitment of condensin to replication origin regions by ParB/SpoOJ promotes chromosome segregation in B. subtilis.
Cell: 2009, 137(4);685-96
[PubMed:19450516] [WorldCat.org] [DOI] (I p)

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed