Difference between revisions of "MntC"
Line 95: | Line 95: | ||
* '''Regulation:''' repressed by Mn(2+) ([[MntR]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/10760146 PubMed] | * '''Regulation:''' repressed by Mn(2+) ([[MntR]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/10760146 PubMed] | ||
+ | ** activated at low Mn(II) concentrations (MntR) [http://www.ncbi.nlm.nih.gov/sites/entrez/10760146 PubMed] | ||
* '''Regulatory mechanism:''' MntR: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/10760146 PubMed] | * '''Regulatory mechanism:''' MntR: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/10760146 PubMed] | ||
+ | ** [[MntR]]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/10760146 PubMed] | ||
* '''Additional information:''' | * '''Additional information:''' |
Revision as of 16:55, 11 June 2009
- Description: manganese ABC transporter (membrane protein)
Gene name | mntC |
Synonyms | ytgC |
Essential | no |
Product | manganese ABC transporter (membrane protein))) |
Function | manganese uptake |
Metabolic function and regulation of this protein in SubtiPathways: Stress | |
MW, pI | 47 kDa, 9.354 |
Gene length, protein length | 1305 bp, 435 aa |
Immediate neighbours | mntD, mntB |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
The gene
Basic information
- Locus tag: BSU30750
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: ABC-3 integral membrane protein family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- Swiss prot entry: O35024
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
John Helmann, Cornell University, USA Homepage
Your additional remarks
References
Q Que, J D Helmann
Manganese homeostasis in Bacillus subtilis is regulated by MntR, a bifunctional regulator related to the diphtheria toxin repressor family of proteins.
Mol Microbiol: 2000, 35(6);1454-68
[PubMed:10760146]
[WorldCat.org]
[DOI]
(P p)