Difference between revisions of "MmgD"

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|style="background:#ABCDEF;" align="center"|'''Function''' || mother cell metabolism  
 
|style="background:#ABCDEF;" align="center"|'''Function''' || mother cell metabolism  
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/carbon_flow.html Central C-metabolism]'''
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 41 kDa, 6.202   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 41 kDa, 6.202   

Revision as of 12:37, 11 June 2009

  • Description: 2-methylcitrate synthase

Gene name mmgD
Synonyms yqiO, prpC
Essential no
Product 2-methylcitrate synthase
Function mother cell metabolism
Metabolic function and regulation of this protein in SubtiPathways:
Central C-metabolism
MW, pI 41 kDa, 6.202
Gene length, protein length 1116 bp, 372 aa
Immediate neighbours mmgE, mmgC
Gene sequence (+200bp) Protein sequence
Genetic context
MmgD context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU24140

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Propanoyl-CoA + H2O + oxaloacetate = (2R,3S)-2-hydroxybutane-1,2,3-tricarboxylate + CoA (according to Swiss-Prot)
  • Protein family: citrate synthase family (according to Swiss-Prot)

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Operon:
  • Regulation: repressed by glucose (CcpA)
  • Regulatory mechanism: CcpA: transcription repression
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed