Difference between revisions of "TrpB"

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=== Basic information ===
 
=== Basic information ===
  
* '''Locus tag:'''
+
* '''Locus tag:''' BSU22640
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
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* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P07600 P07600]
 
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P07600 P07600]
  
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU22640 BSU22640]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU22640]
  
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/4.2.1.20 4.2.1.20]
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/4.2.1.20 4.2.1.20]

Revision as of 10:10, 3 June 2009

  • Description: tryptophan synthase (beta subunit)

Gene name trpB
Synonyms
Essential no
Product tryptophan synthase (beta subunit)
Function biosynthesis of tryptophan
MW, pI 43 kDa, 5.526
Gene length, protein length 1200 bp, 400 aa
Immediate neighbours trpA, trpF
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
TrpB context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU22640

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: L-serine + 1-C-(indol-3-yl)glycerol 3-phosphate = L-tryptophan + glyceraldehyde 3-phosphate + H2O (according to Swiss-Prot)
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulatory mechanism: TRAP: binding to the mRNA in the presence of tryptophan, this results in transcription termination PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed